New models and better data for macromolecular structure determination
For over 50 years, X-ray crystallography has been the foremost method for the determination of three dimensional structures of biological... [mehr]
Rudolf-Virchow-Zentrum für Experimentelle Biomedizin der Universität Würzburg
Megakaryocytes act as „bouncers“ restraining cell migration in the bone marrow
Hematopoiesis is the process of forming blood cells, which occurs predominantly in the bone marrow. The bone marrow produces all types of blood... [mehr]
Substantial differences between the tumor-promoting enzymes USP25 and USP28 identified
The permanent interplay of protein production and degradation is a major driver of cellular metabolism. A key mechanism of this regulation is the... [mehr]
New findings about the molecular effectiveness of the anti-malaria drug artemisinin
Artemisinin is derived from the leaves and flowers of the annual mugwort (Artemisia annua) and has been used in traditional Chinese medicine for... [mehr]
New method gives microscope a boost in resolution
The sharpness of a light microscope is limited by physical conditions: structures that are closer together than 0.2 thousandths of a millimeter... [mehr]
Targeting platelets
"Thrombocytes do much more than to stop bleedings and to cause heart attacks," explains Professor Bernhard Nieswandt, Director of the Institute... [mehr]
New research group at the Rudolf Virchow Center
Proteins are essential components of all known organisms. They are involved in practically every process of life. One of the major challenges life... [mehr]
Protein controls clumping of platelets during thrombosis and stroke
Thus, mice in which the TRPM7 fulfilled only one of its two functions developed significantly less brain damage after a stroke. The paper was... [mehr]