Mouse sperm need a molecular VIP pass to reach the egg membrane
In most animals and plants, the life cycle of an individual begins with fertilisation, when egg and sperm fuse to combine their genetic material.... [mehr]
IMP - Forschungsinstitut für Molekulare Pathologie GmbH
A giant, snake-like enzyme seals the fate of unwanted proteins
Of all molecules that float inside cells, proteins do most of the heavy lifting, yet they can be overzealous at times. To stay healthy, cells... [mehr]
Cross-resistance: when cancer therapy backfires
Battling cancer can be a tricky business. Scientists and clinicians have developed a host of strategies, drugs, and treatments to combat this... [mehr]
Hitting the right note in dialysis care
Our blood carries vital oxygen and nutrients to each of our organs, and transports by-products and toxins that the body needs to eliminate to the... [mehr]
Ready, set, go – or how stem cells synchronise to repair the spinal cord in axolotls
The spinal cord is an important component of our central nervous system: it connects the brain with the rest of the body and plays a crucial part... [mehr]
Disrupting ribosome production – renewed potential for cancer therapy
Proteins are the essence of life: they give structure to cells and organelles, catalyse metabolic reactions, build, break, tug, and pull – they... [mehr]
Harnessing Next Generation Sequencing to detect SARS-CoV-2 and prepare for the next pandemic
The COVID-19 pandemic has lasted more than a year and continues to impact our lives tremendously. Although some countries have launched speedy... [mehr]
Why frogs can’t do it – limb regeneration under the lens
In Lake Xochimilco of central Mexico dwells a rare salamander, the axolotl (Ambystoma mexicanum). In the wild, the axolotls do not metamorphose:... [mehr]
From egg to embryo: how developing zebrafish keep RNA levels in check
At the beginning of an embryo’s development, all cellular processes are regulated by maternal products deposited in the egg, such as RNA... [mehr]