Fountain of youth for ageing stem cells in bone marrow
Epigenetic changes in old age increase risk of osteoporosis and bone fractures - - As we age, our bones become thinner, we suffer fractures... [mehr]
Max-Planck-Institut für Biologie des Alterns
How do our cells react to starvation or stress?
Internal sensor coordinates the cellular stress response to alter the composition of extracellular proteins - - Our cells communicate with... [mehr]
One for all: Convergent mechanism of ageing discovered
Fundamental signalling pathway is crucial for longevity - - Several different causes of ageing have been discovered, but the question remains... [mehr]
Old drug, new target: Rapamycin changes the way our DNA is stored
Researchers discover an unexpected link between DNA winding and metabolism in the gut to ameliorate ageing - - Our genetic material lies in the... [mehr]
DNA building blocks regulate inflammation
Shortage of DNA building blocks in the cell releases mitochondrial DNA - - Our body needs energy - for every metabolic process, every movement... [mehr]
Starved – New drug inhibits the growth of cancer cells
Blocking gene expression in mitochondria in mice stops cancer cells from growing - - Mitochondria provide our cells with energy and cellular... [mehr]
Positive effector behind reduced food intake identified
The Sestrin protein makes fruit flies live longer - - The health benefits of dietary restriction have long been known. Recently, it has become... [mehr]
Small fish populations accumulate harmful mutations that shorten lifespan
Population bottlenecks contribute to the accumulation of several harmful mutations that cause age-related illnesses in killifish – a finding... [mehr]
Nerve cells with energy saving program
In our increasingly ageing society neurodegenerative diseases are posing a significant burden. A growing body of evidence has linked mitochondrial... [mehr]